Orphan Drugs vs Orphan People

Free Market Foundation | July 14, 2014

The World Health Organization (WHO) has declared, "A post-antibiotic era—in which common infections and minor injuries can kill—far from being an apocalyptic fantasy, is instead a very real possibility for the 21st century". With few signs of new drugs becoming available, the rising trend of resistance to antimicrobial pharmaceuticals is one of the most critical and worrying issues facing the global community and has the potential to relegate humanity back to an era not experienced in decades.

With repeated exposure, germs develop resistance to antimicrobials which, eventually, cease to be effective in the treatment of particular illnesses. More and more resistant organisms, which include bacteria, fungi, viruses and some parasites, are withstanding attacks by antimicrobial medicines, such as antibiotics, antifungals, antivirals, and antimalarials, so that treatments are increasingly proving ineffective, allowing infections to persist.
more »

New Tablet Cuts Malaria Pill Burden

A new formulation of the popular anti-malarial drug Coartem has been launched in Kenya.

Researchers Confirm Presence of Malaria Parasite in Bone Marrow

Researchers say they have evidence the malaria parasite lurks in bone marrow, a spongy tissue inside bones where blood cells are produced.

Researchers move closer to disrupting malaria parasite development

Scientists undertaking a "Herculean study" in malaria parasite development recently announced that they are getting closer to disrupting the life-cycle of the parasite—one of the world's deadliest diseases.

Articles

Malaria fight hurt by flimsy anti-DDT research

Last year, Prof Henk Bouwman of North-West University and co-authors published a paper in a respectable journal, Environmental Research, claiming that DDT spraying led to thinning of bird eggshells.

Press Release: DDT research paper exposed as "biased and erroneous"

The environmental science journal Environmental Research has published an article by nine malaria experts exposing major errors in a research paper on DDT and bird eggshells.

Wipe out malaria by wiping out worst poverty

In Southern Africa, the malaria season typically begins with the summer rains in November and ends in April. In this region, the co-ordination of malaria control efforts between neighbouring states has dramatically reduced the incidence of malaria.

Response to "DDT's pesky proponents," by Mara Kardas-Nelson

Al Jazeera's report by Mara Kardas-Nelson (DDT's pesky proponents Apr. 21, 2014) rakes over old ground and is replete with misstatements and falsehoods.

Letter: Climate change clouds SA's plans to eradicate malaria

Claims that climate change will increase the spread of malaria are not new and have been made countless times. Repeatedly making the claim, however, does not make it true.

Read more »

News

New Assay Spots Fake Malaria Drugs

A new assay is inexpensive, simple, and can tell whether or not one of the primary drugs being used to treat malaria is genuine - an enormous and deadly problem in the developing world.

Genetically modified mosquitoes could wipe out malaria

Scientists in Britain believe they have a promising new lead in preventing the transmission of malaria.

Malaria Remains A Threat In Southern Africa

Ministers of Health from Malaria-Endemic Countries meeting in Zimbabwe have adopted the Victoria Falls Declaration in which they commit to eliminate and expand Malaria control to hard-to-reach communities

Malaria Vaccine Tests Making Slow, Sure Progress in Tanzania

Researchers in tropical diseases are focusing developing malaria vaccine trials in Africa, with trails already in progress in Tanzania.

'Smell' of malaria attracts mosquitoes

Malaria may alter the way people smell to make them more alluring to mosquitoes, according to a new study that can help detect the deadly disease non-invasively through body odour.

Read more »

Research & Policies

Pregnancy-associated malaria and malaria in infants: an old problem with present consequences

Albeit pregnancy-associated malaria (PAM) poses a potential risk for over 125 million women each year, an accurate review assessing the impact on malaria in infants has yet to be conducted.

"We have become doctors for ourselves": motives for malaria self-care among adults in southeastern Tanzania

Prompt and appropriate treatment of malaria with effective medicines remains necessary if malaria control goals are to be achieved.

Identification of morphological and chemical markers of dry- and wet-season conditions in female Anopheles gambiae mosquitoes

Increased understanding of the dry-season survival mechanisms of Anopheles gambiae in semi-arid regions could benefit vector control efforts by identifying weak links in the transmission cycle of malaria.

Towards rapid genotyping of resistant malaria parasites: could loop-mediated isothermal amplification be the solution?

Loop-mediated isothermal amplification (LAMP) is an innovative molecular technique that has been validated for point-of-care testing to diagnose malaria.

Field evaluation of four widely used mosquito traps in Central Europe

To monitor adult mosquitoes several trapping devices are available.

Read more »